Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.7
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Thiamin (from Thiamin HCl) (Vitamin B-1)
100 mg
8333%
Riboflavin (Vitamin B-2)
100 mg
7692%
Niacin (Vitamin B-3) (as Niacinamide)
100 mg
625%
Vitamin B-6 (from Pyridoxine HCl)
100 mg
5882%
Folate
680 mcg DFE(400 mcg folic acid)
170%
Vitamin B-12 (as Cyanocobalamin)
100 mcg
4167%
Biotin
100 mcg
333%
Pantothenic Acid (from Calcium Pantothenate)
100 mg
2000%
Choline (from Choline Bitartrate)
35 mg
6%
Inositol
100 mg
†
PABA (Para-Aminobenzoic Acid)
10 mg
†
Top Medical Research Studies
8
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
Read More
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
Read More
8
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Read More
Most Useful Reviews
2
Dosage adjustment needed
5 people found this helpful
I ordered a high dosage for my wife. After taking it for just three days, she experienced constipation and liver pain. While her general condition was good, we plan to reduce the dosage and try again later.
Read More
7.5
Effective for pain
It’s essential to conduct a vitamin B test before ordering and follow a doctor's advice, as deficiency affects the nervous system. After experiencing tendon pain in my right arm, I switched to this product, which proved to be of excellent quality, despite a below-average taste. It may also change urine colour, but I hope it helps.
Read More
7.5
Nervous system support
5 people found this helpful
My eye twitching due to stress and job changes was constant. I decided to take choline and B vitamins to strengthen my nervous system. Although the dosage of choline wasn't daily, it helped somewhat. B vitamins are essential for regulating the nervous system, immune support, and more. The tablets are large, yellow with a riboflavin smell. I recommend buying.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
- All Researches
9
Biotin deficiency mimics neurological disorders
We explored three cases of biotinidase deficiency (BTD) that were misdiagnosed as neuromyelitis optica spectrum disorder (NMOSD) due to similar symptoms and neuroimaging results. Initially, two patients responded to immune therapy but later relapsed, while one showed no improvement. Interestingly, after timely diagnosis and biotin supplementation, two patients exhibited remarkable recoveries in both motor function and vision. This highlights the critical need for accurate diagnosis, as early treatment of BTD can lead to significant improvements.
Read More
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
Read More
8
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
Read More
8
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Read More
7
Vitamin B may indicate GBS severity
We aimed to see if vitamin B levels could signal the severity of Guillain-Barré syndrome (GBS) and its potential for complications like respiratory failure. Our study involved 50 GBS patients, where we examined their vitamin B and creatine kinase levels alongside their motor abilities.
Interestingly, we found that 44% of patients had low vitamin B levels, which linked strongly to GBS severity. However, while vitamin B showed predictive value, the creatine kinase levels did not relate to GBS severity.
Interestingly, we found that 44% of patients had low vitamin B levels, which linked strongly to GBS severity. However, while vitamin B showed predictive value, the creatine kinase levels did not relate to GBS severity.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.7
- All Reviews
- Positive Reviews
- Negative Reviews
2
Dosage adjustment needed
5 people found this helpful
I ordered a high dosage for my wife. After taking it for just three days, she experienced constipation and liver pain. While her general condition was good, we plan to reduce the dosage and try again later.
Read More
7.5
Effective for pain
It’s essential to conduct a vitamin B test before ordering and follow a doctor's advice, as deficiency affects the nervous system. After experiencing tendon pain in my right arm, I switched to this product, which proved to be of excellent quality, despite a below-average taste. It may also change urine colour, but I hope it helps.
Read More
7.5
Nervous system support
5 people found this helpful
My eye twitching due to stress and job changes was constant. I decided to take choline and B vitamins to strengthen my nervous system. Although the dosage of choline wasn't daily, it helped somewhat. B vitamins are essential for regulating the nervous system, immune support, and more. The tablets are large, yellow with a riboflavin smell. I recommend buying.
Read More
7.5
Strength improvement
2 people found this helpful
After contracting COVID, I experienced hair loss and weakness. Previously, I used Solgar's B vitamins with good results, and after three weeks of the same brand, I noticed an increase in strength and reduced hair loss. The change is evident, though the urine does turn bright yellow.
Read More
9
Quality recommendation
The packaging is sturdy, and the product seems stable, providing peace of mind. The delivery was rapid, and customer service was considerate. After using it, I feel improved. The quality is meticulous, ingredients complete, and the taste is acceptable.
Read More
Frequently Asked Questions
7.5
Strength improvement
2 people found this helpful
After contracting COVID, I experienced hair loss and weakness. Previously, I used Solgar's B vitamins with good results, and after three weeks of the same brand, I noticed an increase in strength and reduced hair loss. The change is evident, though the urine does turn bright yellow.
9
Quality recommendation
The packaging is sturdy, and the product seems stable, providing peace of mind. The delivery was rapid, and customer service was considerate. After using it, I feel improved. The quality is meticulous, ingredients complete, and the taste is acceptable.
2
Dosage adjustment needed
5 people found this helpful
I ordered a high dosage for my wife. After taking it for just three days, she experienced constipation and liver pain. While her general condition was good, we plan to reduce the dosage and try again later.
7.5
Nervous system support
5 people found this helpful
My eye twitching due to stress and job changes was constant. I decided to take choline and B vitamins to strengthen my nervous system. Although the dosage of choline wasn't daily, it helped somewhat. B vitamins are essential for regulating the nervous system, immune support, and more. The tablets are large, yellow with a riboflavin smell. I recommend buying.
7.5
Effective for pain
It’s essential to conduct a vitamin B test before ordering and follow a doctor's advice, as deficiency affects the nervous system. After experiencing tendon pain in my right arm, I switched to this product, which proved to be of excellent quality, despite a below-average taste. It may also change urine colour, but I hope it helps.
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
8
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
8
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
References
- Jatav VS, Sardana V, Bhushan B, Maheshwari D, Garg S, et al. Correlation of Serum Vitamin B and Muscle Enzyme (CK-NAC) Level with Severity of Guillain-Barre Syndrome and Its Prediction in Respiratory Failure. J Assoc Physicians India. 2025;73:48. doi:10.59556/japi.73.0892
- Mesgarankarimi A, Rezapour M, Tabrizi N. A long-standing undiagnosed case of vitamin B12 deficiency: a case report. J Med Case Rep. 2025;19:151. doi:10.1186/s13256-025-05149-7
- Mswelo VE, David MM, Banturaki A, Munyambalu DK, Hassan HA, et al. Rural health challenges in Western Uganda: pernicious anemia masquerading as recurrent lower limb weakness-a case report. J Med Case Rep. 2025;19:60. doi:10.1186/s13256-025-05095-4
- Cao AP, Wang YY, Shen YY, Liu YH, Liu JY, et al. Nicotinamide Suppresses Hyperactivation of Dendritic Cells to Control Autoimmune Disease through PARP Dependent Signaling. Nutrients. 2024;16. doi:10.3390/nu16162665
- Ali F, Mukhtiar K, Raza M, Ibrahim S. Atypical presentation of biotinidase deficiency: masquerading neuromyelitis optica spectrum disorder. BMJ Case Rep. 2024;17. doi:10.1136/bcr-2023-258703
